Single Cell Atlas: a single-cell multi-omics human cell encyclopedia.

> 商业许可源文 · EUROPE_PMC · [CC-BY](https://creativecommons.org/licenses/by/)

书目信息

引用：Pan L, Parini P, Tremmel R, Loscalzo J, Lauschke VM, Maron BA, Paci P, Ernberg I, Tan NS, Liao Z, Yin W, Rengarajan S, Li X, SCA Consortium. (2024). Single Cell Atlas: a single-cell multi-omics human cell encyclopedia. Genome biology. PMID 38641842 · PMC11027364 · DOI 10.1186/s13059-024-03246-2

证据类型：DATABASE_RESOURCE

主题：rna-seq、single-cell、epigenomics、multi-omics、spatial-omics

被引次数（采集时）：36

原始记录：[Europe PMC](https://europepmc.org/article/MED/38641842)

来源许可：[CC-BY](https://creativecommons.org/licenses/by/)

作者摘要（按来源许可复用）

Single-cell sequencing datasets are key in biology and medicine for unraveling insights into heterogeneous cell populations with unprecedented resolution. Here, we construct a single-cell multi-omics map of human tissues through in-depth characterizations of datasets from five single-cell omics, spatial transcriptomics, and two bulk omics across 125 healthy adult and fetal tissues. We construct its complement web-based platform, the Single Cell Atlas (SCA, www.singlecellatlas.org ), to enable vast interactive data exploration of deep multi-omics signatures across human fetal and adult tissues. The atlas resources and database queries aspire to serve as a one-stop, comprehensive, and time-effective resource for various omics studies.

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